Ace The SPEX Exam

Be prepared for the Federation of State Medical Boards® with 6,700 Questions that our experts have selected to simulate the real exam.

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About the Question Bank

Our review is designed to help you maximize your score on the SPEX Exam. StatPearls questions and articles are based on our experts review of the Federation of State Medical Boards® topics. Each review course is designed to empower you to assess your knowledge and understanding of medical principles and concepts found on the SPEX Exam.

Multiple-choice questions

We have 6,700 Multiple-choice 1st, 2nd, and 3rd order questions with four detailed teaching points linked to 3,702 PubMed indexed review articles related to the SPEX Examination. You can customize practice questions to anatomical and clinical SPEX Student subject areas. In addition, you will have access to a pre- and post-test SPEX Exam to help you target learning and identify areas that need further study. Analytics and reports allow you to compare your scores to other students.

Achieve top scores

The StatPearls SPEX prep questions, SPEX review questions, and SPEX test questions will help you achieve a top score on the SPEX Examination. 3,007 authors and 46 editors have contributed to the development of the SPEX Exam content, which is continuously refined and updated to improve your learning experience.

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SPEX Exam Overview

  • How many hours is the SPEX Exam?

    The SPEX Exam is 6 hours.

  • How many questions is the SPEX Exam?

  • What topics are covered on the SPEX Exam?

SPEX Exam MCQs (6,700)

Our question bank for the SPEX Exam covers four Cognitive Difficulty Levels:

Level 1

39 Questions

Level 2

647 Questions

Level 3

4,783 Questions

Level 4

1,231 Questions

  • Allergy and Immunology - 332 questions
  • Cardiovascular - 1621 questions
  • Connective Tissue - 198 questions
  • Ears Nose and Throat - 347 questions
  • Endocrine and Metabolic - 859 questions
  • Eyes - 277 questions
  • Gastrointestinal - 1307 questions
  • Genetics - 215 questions
  • Genitourinary - 371 questions
  • Growth and Development - 265 questions
  • Gynecologic - 269 questions
  • Hematologic - 538 questions
  • Infectious - 1695 questions
  • Integument - 639 questions
  • Musculoskeletal - 1049 questions
  • Nervous - 1479 questions
  • Nutrition - 174 questions
  • Obstetric - 270 questions
  • Oncologic - 694 questions
  • Psychiatric Mental Health - 506 questions
  • Pulmonary - 970 questions
  • Renal - 451 questions
  • Surgery - 635 questions
  • Toxicology - 496 questions
  • Trauma, Injury, Safety, and Violence - 703 questions
  • Teeth/Oral - 31 questions
  • Reproductive - 44 questions
  • Sexuality and Gender - 20 questions
  • Psychiatric Addiction - 68 questions
  • Pharmacology - 540 questions
  • Thoracic - 110 questions
  • Anatomy - 87 questions
  • Behavioral - 77 questions
  • Histology - 8 questions
  • Neuroanatomy - 100 questions
  • Pathology - 187 questions
  • Biochemistry - 11 questions
  • Physiology - 185 questions
  • Embryology - 9 questions
  • Cell Biology - 7 questions
  • Manage Care and Comply Regulations - 154 questions
  • Promote Safety and Minimize Infection - 143 questions
  • Health Promotion & Maintenance (Prevent Problems) - 386 questions
  • Basic Care and Comfort (Assist Daily Living Tasks) - 47 questions
  • Pharm/Parenteral Therapy (Drugs/Vital Signs) - 1185 questions
  • Reduction Risk (Post Procedure) - 111 questions
  • Physiological Adaptation (Care Ill Patients) - 4590 questions
  • Psychosocial (Mental Health Patient/Family) - 353 questions
  • Professional Practice - 138 questions
  • Process (Analysis, Assess, Eval, Implement, Plan) - 5721 questions
  • Caring (Hope and Support) - 49 questions
  • Communication/Documentation (Oral, Written, EMR) - 56 questions
  • Teaching/Learning (Promotes Behavior Change) - 68 questions
  • Culture/Spiritualilty (Beliefs, Practices, Ethics) - 22 questions
  • Causes - 3747 questions
  • Classification - 596 questions
  • Differential - 3693 questions
  • Epidemiology - 227 questions
  • Evaluation Diagnostic Tests - 1972 questions
  • Evaluation Lab - 2227 questions
  • Evaluation Monitoring - 565 questions
  • Evaluation Nuclear Medicine - 21 questions
  • Evaluation Procedures - 1236 questions
  • Evaluation Radiologic - 1917 questions
  • Health Maint Prevention Public Health - 281 questions
  • History Physical - 7695 questions
  • Legal - 52 questions
  • Pathophysiology - 3838 questions
  • Patient Education - 444 questions
  • Prognosis Complications - 3864 questions
  • Toxicology - 372 questions
  • Treatment Medical - 3684 questions
  • Treatment Occupation/Physical Therapy - 70 questions
  • Treatment Prehospital/EMS/Disaster - 55 questions
  • Treatment Radiation - 30 questions
  • Treatment Rehabilitation - 41 questions
  • Treatment Surgical - 789 questions
  • Healthcare Ethics - 64 questions
  • Clinical Education - 102 questions
  • Environmental - 15 questions
  • Palliative - 23 questions
  • Treatment Manipulative - 8 questions
  • Airway Management - 32 questions
  • Pain Management - 73 questions
  • Sedation and Analgesic Management - 16 questions
  • Organ and Tissue Donation - 2 questions
  • Ventilatory Management - 17 questions
  • Biostatistics - 5 questions
  • Research and Evidence-Based Medicine - 45 questions
  • Resource Utilization - 11 questions
  • Vulnerable Populations - 64 questions
  • Therapeutics (Drug treatment) - 1611 questions
  • Biostatics and Calculations - 12 questions
  • Drug Information - 1072 questions
  • Pharmaceutics (Safely dosing medications) - 459 questions
  • Pharmacokinetics (Drug movement in body) - 206 questions

SPEX Exam Articles (3,702)

We link each review question to its peer-reviewed, PubMed-indexed article from StatPearls authors and editors.
We make it easy for you to reinforce topic areas you excel at and fill knowledge gaps with source material.