Warfarin Drug Interactions

Overview

4.7 out of 5 (57 Reviews)

Credits

1.50

Post Assessment Questions

10

Start Date

1 Sep 2023

Last Review Date

1 Sep 2023

Expiration Date

31 Aug 2026

Estimated Time To Finish

90 Minutes


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Activity Description

Warfarin has FDA approval for the prophylaxis and treatment of venous thrombosis and its complications, such as a pulmonary embolus. It is also indicated to prevent thromboembolic complications associated with conditions such as atrial fibrillation, cardiac valve replacement, and inherited genetic factors like C and S protein deficiency or Factor V Leiden. Additionally, warfarin is FDA approved as an adjunct to reduce the risk of myocardial infarction (MI) and other thromboembolic events in high-risk patients. However, warfarin falls in the narrow therapeutic index drug category and is subject to numerous interactions. This activity outlines the indications, mechanism of action, interactions, significant adverse effects, contraindications, toxicity, and warfarin monitoring so providers can direct patient therapy where anticoagulation is indicated as part of the interprofessional team.

Target Audience

This activity has been designed to meet the educational needs of physicians, physician associates, nurses, pharmacists, and nurse practitioners.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Identify the mechanism of action of warfarin.
  • Review the agents that can either increase or decrease the anticoagulant effect of warfarin.
  • Summarize the target INR levels for warfarin therapy based on conditions that affect INR targets.
  • Describe the importance of collaboration and coordination among the interprofessional team and how it can enhance patient care with warfarin therapy in conjunction with the patient's entire medication regimen to improve patient outcomes for patients with conditions where anticoagulation is indicated.

Disclosures

StatPearls, LLC requires everyone who influences the content of an educational activity to disclose relevant financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. All relevant conflict(s) of interest have been mitigated. Hover over contributor names for financial disclosures. Others involved in planning this educational activity have no relevant financial relationships to disclose.

Commercial Support: This activity has received NO commercial support.

Continuing Education Accreditation Information

In support of improving patient care, StatPearls, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

 

Nurses: StatPearls designates this activity for 1.50 ANCC contact hour(s). Nurses should only claim credit commensurate with the extent of their participation in the activity.

Please consult your professional licensing board for information on the applicability and acceptance of continuing education credit for this activity.

Method of Participation and Credit

  1. Register for the activity.    
  2. Review the target audience, learning objectives, and disclosure information.
  3. Study the educational content of the enduring material.
  4. Choose the best answer to each activity test question. To receive credit and a certificate, you must pass the test questions with a minimum score of 100%.
  5. Complete the post-activity assessment survey.

If you have concerns regarding the CE/CME system, please contact support@statpearls.com.

Disclaimer

This educational activity was planned and produced in accordance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education. Faculty may discuss investigational products or off-label uses of products regulated by the US Food and Drug Administration. Readers should verify all information before employing any therapies described in this educational activity.

The information provided for this activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition. The information presented does not necessarily reflect the views of StatPearls or any commercial supporters of educational activities on statpearls.com. StatPearls expressly disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through a participant's misunderstanding of the content.

Unapproved Uses of Drugs/Devices: In accordance with FDA requirements, the audience is advised that information presented in this continuing education activity may contain references to unlabeled or unapproved uses of drugs or devices. Please refer to the FDA-approved package insert for each drug/device for full prescribing/utilization information.

Cancellation Policy: Please see the cancellation policy. StatPearls, LLC reserves the right to cancel any course due to unforeseen circumstances.

 

 
 

Reviews

Valentine C. on 4/14/2021

Edward I. on 7/31/2021

Barbara C. on 8/17/2021

Peggy K. on 9/14/2021

marshall s. on 12/4/2021

Stephen M. on 12/29/2021

Basil R. on 1/5/2022

Mary Y. on 3/16/2022

Lori N. on 4/16/2022

Emmy K. on 5/11/2022

Christine D. on 5/16/2022

Emily V. on 6/30/2022

Noah S. on 7/28/2022

Kathryn C. on 8/22/2022

Alex N. on 8/30/2022

Amanda F. on 9/12/2022

Rayon S. on 11/16/2022

Tara D. on 12/8/2022

Great

Kenneth R. on 12/10/2022

Kecia T. on 12/24/2022

Nicole M. on 12/31/2022

Deborah M. on 1/8/2023

Lisa B. on 1/30/2023

Christine G. on 3/14/2023

Amy A. on 4/7/2023

Nicole S. on 5/3/2023

Expand this course to include more drugs and icrease CEUs to 3.

JAMI W. on 5/27/2023

would be helpful to have a more comprehensive list/table of drug interactions w/warfarin.

Angela D. on 6/6/2023

Leah S. on 6/12/2023

VLADIMIR E. on 6/29/2023

Terry P. on 8/19/2023

Rey V. on 8/17/2023

Van J. on 8/22/2023

Yan L. on 9/28/2023

Matthew V. on 10/11/2023

Christopher E. on 11/2/2023

SUSAN L. on 11/5/2023

Jennifer L. on 11/13/2023

Sarah G. on 11/22/2023

SAMER E. on 11/30/2023

MICHELLE B. on 12/4/2023

Jakob H. on 12/29/2023

Erika B. on 12/29/2023

camille j. on 1/3/2024

Stephen B. on 1/1/2024

mary m. on 2/17/2024

Louie L. on 2/25/2024

Janet P. on 3/19/2024

Kathleen K. on 3/29/2024

Alison D. on 4/29/2024

Joseph G. on 4/30/2024

Glenn F. on 6/6/2024

Hilina y. on 6/22/2024

Cathryn C. on 6/26/2024

debbie s. on 11/10/2023

Kimberly R. on 11/1/2023

Karen M. on 7/14/2024

Unlimited Nurse CE

Stay up to date on the latest medical knowledge with 6670 CE activities. In these online self-assessment activities, read our reference articles and test your knowledge with more than 7922 hours of CE.

1 Year Unlimited Nurse CE

Access to all the Unlimited Nurse CE activities in all specialties.

$39.99 per 1 year per user