Introduction
The mandible is the largest bone in the human skull, forming the lower jawline and shaping the contour of the inferior third of the face.[1] Articulation with the skull base at the bilateral temporomandibular joints allows a range of movements facilitated by associated muscles, including dental occlusion with the maxilla. The mandible is also the insertion point for a range of muscles involved in facial expression. Mandible fractures are relatively common in trauma, particularly among young males, and half are caused by interpersonal violence.[2]
Structure and Function
Register For Free And Read The Full Article
- Search engine and full access to all medical articles
- 10 free questions in your specialty
- Free CME/CE Activities
- Free daily question in your email
- Save favorite articles to your dashboard
- Emails offering discounts
Learn more about a Subscription to StatPearls Point-of-Care
Structure and Function
The mandible is made up of a U-shaped body that projects anteroposteriorly. At the posterior ends of the body are the bilateral gonial angles, from which the rami extend vertically towards the articulation with the cranial base.[3]
Body
The body of the mandible is the horizontal U-shaped portion of the mandible. The mandibular symphysis is found anteriorly in the midline, where the two constituent fetal bones fuse after birth.[4] This is palpable as a small vertical ridge in the adult, which inferiorly splits to enclose a midline depression termed the mental protuberance, the edges of which are the mental tubercles. From the mental tubercles, the external oblique line runs posteriorly to the anterior border on the ramus.
The superior surface of the mandibular body consists of alveolar bone, is lined with tooth sockets, and is covered with mucoperiosteum, which forms the gingivae.
The bilateral mental foramina are an important landmark on the external mandibular surface, as it allows access to the mental nerve for a local anesthetic block. This landmark lies halfway between the upper and lower borders of the mandibular body, most commonly on the imaginary line which would run between the first and second premolars, although this varies with age.[5]
The internal surface of the body is crossed obliquely by the mylohyoid line that starts from just below the posterior border of the third molar and runs anteroinferiorly to fade into the midline.[6] Below the middle part of the mylohyoid line lies the smooth submandibular fossa, which contains part of the submandibular gland. Further anteriorly, close to the midline, the sublingual fossa lies above the mylohyoid line and contains the sublingual gland.
In the midline of the internal surface of the mandibular body are four mental spines, which serve as attachments for intrinsic tongue muscles.[7] Finally, two rounded depressions termed the digastric fossae can be found just laterally to the midline, where the anterior bellies of the digastric muscle attach.
Ramus
The ramus contributes to the lateral portion of the mandible on either side. The anterior border of the ramus terminates superiorly as the coronoid process and the posterior border as the condyle or head of the mandible. The smooth concave mandibular notch separates the two. The condyle of the mandible contributes to the temporomandibular joint, with a biconcave fibrocartilaginous disc intervening between the condyle and the mandibular fossa of the temporal bone.[8]
The lateral surface of the ramus contains a portion of the oblique line, which begins on the external surface of the body inferiorly. This surface also provides the origin for the masseter muscle.
The internal surface of the ramus is punctured by the mandibular foramen, situated halfway between the anterior and posterior borders of the ramus at the level of the occlusal surfaces of the lower teeth, and through which the inferior alveolar nerve and vessels enter the mandibular canal, ultimately terminating at the mental foramen.[9] The lingula is a small flap of bone that overlies the anterior part of the mandibular foramen, to which the sphenomandibular ligament attaches.[10] The mylohyoid groove is an inferior continuation from the lingula, through which the mylohyoid nerve and vessels travel after piercing the sphenomandibular ligament.
The coronoid process is located at the superior aspect of the ramus. Its anterior border is continuous with that of the ramus, and its posterior border creates the anterior boundary of the mandibular notch. The temporalis muscle and masseter insert on its lateral surface.
The condyloid process is also located at the superior aspect of the ramus and is divided into two parts, the neck and the condyle. The neck is the thinner portion of the condyloid process that projects from the ramus. The condyle is the most superior portion and contributes to the temporomandibular junction by articulating with the articular disk.[8]
Embryology
During the sixth week of intrauterine development, the mandible is the second bone to ossify, following the clavicle.[11] The first pharyngeal arch, the mandibular arch, gives rise to the Meckel cartilage. This cartilage serves as a template for the development of the mandible. A fibrous membrane covers the left and right Meckel cartilage at their ventral ends, each of which gives rise to a single ossification center. These two halves eventually fuse via fibrocartilage at the mandibular symphysis. Thus, the mandible is still composed of two separate bones at birth. Ossification and fusion of the mandibular symphysis occur during the first year of life, resulting in a single bone. The remnant of the mandibular symphysis is a subtle ridge at the midline of the mandible.[11]
The mandible constantly changes throughout life. At birth, the gonial angle is approximately 160 degrees. By age four, teeth have formed, causing the jaw to elongate and widen; these changes in the mandible's dimensions cause the gonial angle to decrease to approximately 140 degrees. By adulthood, the gonial angle is reduced to approximately 120 degrees.[11]
Blood Supply and Lymphatics
Blood supply to the mandible is via small periosteal and endosteal vessels. The periosteal vessels arise mainly from the inferior alveolar artery and supply the ramus of the mandible. The endosteal vessels arise from the peri-mandibular branches of the maxillary artery, facial artery, external carotid artery, and superficial temporal artery; these supply the body of the mandible.[12] Dental branches from the inferior alveolar artery supply the mandibular teeth.
Lymphatic drainage of the mandible and mandibular teeth is primarily via the submandibular lymph nodes. However, the mandibular symphysis region drains into the submental lymph node, which subsequently drains into the submandibular nodes.
Nerves
The main nerve associated with the mandible is the inferior alveolar nerve, a branch of the mandibular division of the trigeminal nerve. The inferior alveolar nerve enters the mandibular foramen and courses anteriorly in the mandibular canal, sending branches to the lower teeth and providing sensation. At the mental foramen, the inferior alveolar nerve branches into the incisive and mental nerve. The mental nerve exits the mental foramen and courses superiorly to provide sensation to the lower lip. The incisive nerve runs in the incisive canal, providing innervation to the mandibular premolar, canine, and lateral and central incisors.[13]
Muscles
Muscles Originating from the Mandible
- Mentalis - originates from the incisive fossa
- Orbicularis oris - originates from the incisive fossa
- Depressor labii inferioris - originates from the oblique line
- Depressor anguli oris - originates from the oblique line
- Buccinator - originates from the alveolar process
- Digastric anterior belly - originates from the digastric fossa
- Mylohyoid - originates from the mylohyoid line
- Geniohyoid - originates from the inferior portion of the mental spine
- Genioglossus - originates from the superior portion of the mental spine
- Superior pharyngeal constrictor - originates partially from the pterygomandibular raphe, which originates from the mylohyoid line
Muscles Inserting on the Mandible
- Platysma - inserts on the inferior border of the mandible
- Superficial masseter - inserts on the lateral surface of the ramus and angle of the mandible
- Deep masseter - inserts on the lateral surface of the ramus and angle of the mandible
- Medial pterygoid - inserts on the medial surface of the mandibular angle and ramus of the mandible
- Inferior head of the lateral pterygoid - inserts on the condyloid process
- Temporalis - inserts on the coronoid process
Physiologic Variants
Males generally have squarer, more prominent mandibles than females. This is due to the larger size of the mental protuberance in males and the decreased gonial angle. The gonial angle is 90 degrees in males, compared to 110 in females.
A bifid or trifid inferior alveolar canal may be present in rare instances. This can be detected on X-ray as a second or third mandibular canal. Branches of the inferior alveolar nerve commonly run through these extra foramina and can confer a risk for inadequate anesthesia during surgical procedures involving the mandible.[14]
A cleft chin can result from the inadequate or absent fusion of the mandibular symphysis during embryonic development. This often results in a depression of the overlying soft tissue at the midline of the mandible. This is a genetic condition that is inherited in an autosomal dominant fashion and found more frequently in the male population.[15]
Surgical Considerations
Orthognathic surgery, which includes mandible osteotomies and sagittal split osteotomies, is corrective jaw surgery performed to improve bite malalignment, sleep apnea, temporomandibular joint disorders, and structural issues such as cleft palate and micrognathia.
Mandible osteotomy is performed on patients with micrognathia, a condition in which the mandible is undersized. Micrognathia may result in pain and difficulty chewing; correction is often needed. This procedure is performed by transecting the mandible between the first and second molars bilaterally; the mandible is extended into its new position and stabilized with hardware.
Sagittal split osteotomy is performed on patients with prognathism, in which the mandible is oversized, causing an underbite. This procedure is performed by transecting the mandible bilaterally, repositioning it in a more posterior position, and stabilizing it with hardware.
Complications of these procedures include postoperative facial numbness due to nerve damage. Recovery from nerve damage typically occurs within three months of the procedure.
Clinical Significance
Mandibular fractures are most commonly caused by trauma and typically occur in two places. The parasymphysis is especially prone to fracture due to the incisive fossa and mental foramen. A direct blow to the mandible may cause a condylar neck fracture as the articular disk of the temporomandibular joint prevents it from moving posteriorly.[16]
A standard four-view series of X-ray films may be obtained in patients with traumatic mandibular injuries. Due to superimposed anatomy, mandibular series often do not provide sufficient detail to accurately diagnose condylar fractures. This issue is solved by using a reversed Towne view for imaging. Newer modalities such as CT scans have proven more sensitive than X-rays and are commonly employed.[17]
Dislocation of the mandible is most frequently in the posterior direction, but anterior and inferior dislocations may be observed. The patient may be unable to close their mouth or have an asymmetric jawline. Previous dislocation is the most significant risk factor. Manual reduction is often used to correct the injury. Barton bandages are used after reduction to hold the jaw in place and provide stabilization.
Other Issues
The mandible is a vital bone in terms of forensic evidence. Because the mandible progressively changes over an individual's life, it is routinely used to determine the age of the deceased.
Media
(Click Image to Enlarge)
(Click Image to Enlarge)
Medial Aspect of Jaw Anatomy. Jaw anatomy includes the mandible, capsular ligament, spine of the sphenoid, styloid process, stylomandibular ligament, mandible foramen, and mylohyoid groove.
Henry Vandyke Carter, Public Domain, via Wikimedia Commons
(Click Image to Enlarge)
(Click Image to Enlarge)
References
Reece EM, Rohrich RJ. The aesthetic jaw line: management of the aging jowl. Aesthetic surgery journal. 2008 Nov-Dec:28(6):668-74. doi: 10.1016/j.asj.2008.09.007. Epub [PubMed PMID: 19083596]
Lee KH. Epidemiology of mandibular fractures in a tertiary trauma centre. Emergency medicine journal : EMJ. 2008 Sep:25(9):565-8. doi: 10.1136/emj.2007.055236. Epub [PubMed PMID: 18723703]
Upadhyay RB, Upadhyay J, Agrawal P, Rao NN. Analysis of gonial angle in relation to age, gender, and dentition status by radiological and anthropometric methods. Journal of forensic dental sciences. 2012 Jan:4(1):29-33. doi: 10.4103/0975-1475.99160. Epub [PubMed PMID: 23087579]
Al-Khateeb SN, Al Maaitah EF, Abu Alhaija ES, Badran SA. Mandibular symphysis morphology and dimensions in different anteroposterior jaw relationships. The Angle orthodontist. 2014 Mar:84(2):304-9. doi: 10.2319/030513-185.1. Epub 2013 Aug 5 [PubMed PMID: 23914822]
Kqiku L, Sivic E, Weiglein A, Städtler P. Position of the mental foramen: an anatomical study. Wiener medizinische Wochenschrift (1946). 2011 May:161(9-10):272-3. doi: 10.1007/s10354-011-0898-2. Epub [PubMed PMID: 21638218]
Level 2 (mid-level) evidenceRyu EJ, Kim DH. Anatomical insights of the mylohyoid for clinical procedures in dentistry. Clinical anatomy (New York, N.Y.). 2021 Apr:34(3):461-469. doi: 10.1002/ca.23675. Epub 2020 Sep 21 [PubMed PMID: 32893917]
Singh V, Anand MK, Dinesh K. Variations in the pattern of mental spines and spinous mental foramina in dry adult human mandibles. Surgical and radiologic anatomy : SRA. 2000:22(3-4):169-73 [PubMed PMID: 11143309]
Alomar X, Medrano J, Cabratosa J, Clavero JA, Lorente M, Serra I, Monill JM, Salvador A. Anatomy of the temporomandibular joint. Seminars in ultrasound, CT, and MR. 2007 Jun:28(3):170-83 [PubMed PMID: 17571700]
Kilic C, Kamburoğlu K, Ozen T, Balcioglu HA, Kurt B, Kutoglu T, Ozan H. The position of the mandibular canal and histologic feature of the inferior alveolar nerve. Clinical anatomy (New York, N.Y.). 2010 Jan:23(1):34-42. doi: 10.1002/ca.20889. Epub [PubMed PMID: 19918867]
Garg A, Townsend G. Anatomical variation of the sphenomandibular ligament. Australian endodontic journal : the journal of the Australian Society of Endodontology Inc. 2001 Apr:27(1):22-4 [PubMed PMID: 11481875]
Lipski M, Tomaszewska IM, Lipska W, Lis GJ, Tomaszewski KA. The mandible and its foramen: anatomy, anthropology, embryology and resulting clinical implications. Folia morphologica. 2013 Nov:72(4):285-92 [PubMed PMID: 24402748]
Level 3 (low-level) evidenceSaka B, Wree A, Henkel KO, Anders L, Gundlach KK. Blood supply of the mandibular cortex: an experimental study in Göttingen minipigs with special reference to the condyle. Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery. 2002 Feb:30(1):41-5 [PubMed PMID: 12064882]
Level 3 (low-level) evidenceLee MH, Kim HJ, Kim DK, Yu SK. Histologic features and fascicular arrangement of the inferior alveolar nerve. Archives of oral biology. 2015 Dec:60(12):1736-41. doi: 10.1016/j.archoralbio.2015.09.007. Epub 2015 Sep 11 [PubMed PMID: 26433190]
Wadhwani P, Mathur RM, Kohli M, Sahu R. Mandibular canal variant: a case report. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology. 2008 Feb:37(2):122-4. doi: 10.1111/j.1600-0714.2007.00573.x. Epub [PubMed PMID: 18197857]
Level 3 (low-level) evidenceLadani P, Sailer HF, Sabnis R. Tessier 30 symphyseal mandibular cleft: early simultaneous soft and hard tissue correction - a case report. Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery. 2013 Dec:41(8):735-9. doi: 10.1016/j.jcms.2012.12.009. Epub 2013 Feb 28 [PubMed PMID: 23454264]
Level 3 (low-level) evidenceMorrow BT, Samson TD, Schubert W, Mackay DR. Evidence-based medicine: Mandible fractures. Plastic and reconstructive surgery. 2014 Dec:134(6):1381-1390. doi: 10.1097/PRS.0000000000000717. Epub [PubMed PMID: 25415101]
Gupta M, Iyer N, Das D, Nagaraj J. Analysis of different treatment protocols for fractures of condylar process of mandible. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons. 2012 Jan:70(1):83-91. doi: 10.1016/j.joms.2011.02.009. Epub 2011 May 6 [PubMed PMID: 21549492]